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Cost-free and conjugated noroxycodone, free and conjugated oxycodone, and oxymorphone are excreted in human urine adhering to just one oral dose of oxycodone. The foremost circulating metabolite is noroxycodone with the AUC ratio of 0.six relative to that of oxycodone. Oxymorphone is present from the plasma only in reduced concentrations. The analg